An annual event which is always held byKawasaki Disease Foundation, this year is held at the end of the 2011. The respectful event is held every year to collect charity which is also known as “To Save a Children’s Heart. This event has been held for the third time with this year which is held in San Diego. The program is expected to continue and give contribution for children health betterment. Many guests around the world are invited to this event and this year there are about 255 guests across nations attend this Kawasaki Disease event. Apart from the charity that is the main objective of this event, culinary and other performances are also exhibited here.
Culinary becomes central attraction of this year Kawasaki Disease
The guests who are attending this year Kawasaki Disease annual event are guaranteed to be joyful since one of the main enjoyments is the chance to taste world class culinary. The guests have fortunate chance to taste four courses of gourmet food which were prepared for them by one of 15 nationally acclaimed chefs which were prepared at their table. Among those chefs were Nate Appleman, William Bradley, Roy Choi, and many other famous chefs. The guests of this Kawasaki Disease event this year surely had their appetite spoiled with tasteful foods of highest quality.
The guests who are attending this year Kawasaki Disease annual event are guaranteed to be joyful since one of the main enjoyments is the chance to taste world class culinary. The guests have fortunate chance to taste four courses of gourmet food which were prepared for them by one of 15 nationally acclaimed chefs which were prepared at their table. Among those chefs were Nate Appleman, William Bradley, Roy Choi, and many other famous chefs. The guests of this Kawasaki Disease event this year surely had their appetite spoiled with tasteful foods of highest quality.
Kawasaki Disease is expected to be a continuous event
Many helps and researches for humanity had been realized thanks to Kawasaki Disease foundation. The supports for this event had been given by many people and other groups in many forms. Some efforts are also done to attract many people to participate in this event including inviting stars and also giving prize like American Idol final ticket and chances to have dinner together with the foundation leaders. Kawasaki Disease events are expected to be held in the following years in many other countries.
Many helps and researches for humanity had been realized thanks to Kawasaki Disease foundation. The supports for this event had been given by many people and other groups in many forms. Some efforts are also done to attract many people to participate in this event including inviting stars and also giving prize like American Idol final ticket and chances to have dinner together with the foundation leaders. Kawasaki Disease events are expected to be held in the following years in many other countries.
History
Kawasaki syndrome (KS), also known as Kawasaki disease, is an acute febrile illness of unknown etiology that primarily affects children younger than 5 years of age. KS was first described in Japan by Tomisaku Kawasaki in 1967, and the first cases outside of Japan were reported in Hawaii in 1976.
KS occurs worldwide, with the highest incidence in Japan, and it most often affects boys and younger children. KS may have a winter-spring seasonality, and community-wide outbreaks have been reported occasionally. In the continental United States, population-based and hospitalization studies have estimated an incidence of KS ranging from 9 to 19 per 100,000 children younger than 5 years of age. Approximately 4248 hospitalizations with KS, of which 3277 (77%) were for children under 5 years of age, were estimated among children younger than 18 years of age in the United States in the year 2000. In 2006, the number of hospitalizations with KS was 5523 (standard error [SE] 289) and the percentage of children under 5 years of age remained the same.
SOURCE: CDC
What is Kawasaki's disease?
Kawasaki's disease is an uncommon illness in children that is characterized by high fever of at least five days' duration together with at least four of the following five findings:
- Inflammation with reddening of the whites of the eyes (conjunctivitis) without pus
- Redness or swelling of the hands or feet, or generalized skin peeling
- Rash
- Lymph node swelling in the neck
- Cracking inflamed lips or throat, or red "strawberry" tongue
The above criteria are used to make a diagnosis of Kawasaki's disease. The terminology "incomplete Kawasaki's disease" is sometimes used for patients with only some features of classical Kawasaki's disease.
What is mucocutaneous lymph node syndrome?
Mucocutaneous lymph node syndrome is the original name for Kawasaki's disease. The original name was quite descriptive because the disease is characterized by the typical changes in the mucous membranes that line the lips and mouth and by the enlarged and tender lymph nodes.
What are the usual symptoms and signs of Kawasaki's disease?
The usual symptoms and signs of Kawasaki's disease include
- fever,
- reddening of the eyes,
- cracked and inflamed lips and mucous membranes of the mouth with an inflamed "strawberry" tongue,
- ulcerative gum disease (gingivitis),
- swollen lymph nodes in the neck (cervical lymphadenopathy),
- and a rash that is raised and bright red.
The rash appears in a glove-and-sock fashion over the skin of the hands and feet. The rash becomes hard, swollen (edematous), and then peels off.
What are the less common findings?
Most of the common symptoms described above will resolve without complications, even if untreated. Less common findings include inflammation of the lining of the heart (pericarditis), joints (arthritis), or covering of the brain and spinal cord (meningitis), and the other heart complications listed below in the section on serious complications. The outlook (prognosis) for an individual affected is primarily determined by the seriousness of any heart complications.
What is the difference between Kawasaki's disease and Kawasaki's syndrome?
They are the same. Kawasaki's disease is also referred to as Kawasaki's syndrome. It was first described in the late 1960s in Japan by the pediatrician Tomisaku Kawasaki.
What causes Kawasaki's disease?
The cause is not known. Microorganisms and toxins have been suspected, but none has been identified to date. Kawasaki's disease is not felt to be a contagious illness. Genetic factors and the immune system seem to play roles in the disease, which is characterized by immune activation.
Who develops Kawasaki's disease?
Kawasaki disease typically affects children under 5 years of age. Only rarely does it affect children over 8 years of age, in which case it is sometimes referred to as atypical Kawasaki's disease.
How can Kawasaki's disease cause serious complications?
Children with Kawasaki's disease can develop inflammation of the arteries of various parts of the body. This inflammation of the arteries is called vasculitis. Arteries that can be affected include the arteries that supply blood to the heart muscle (the coronary arteries). Vasculitis can cause weakening of the blood vessels and lead to areas of vessel widening (aneurysms). Coronary aneurysms have been reported in up to 25% of those with Kawasaki's disease.
Because of the potential for heart injury and coronary aneurysms, special tests are performed to examine the heart. Children are typically evaluated with an electrocardiogram (EKG) and an ultrasound test of the heart (echocardiogram). Other arteries that can become inflamed include the arteries of the lungs, neck, and abdomen. These effects can lead to breathing problems, headaches, and pain in the belly, respectively.
What is the treatment for Kawasaki's disease?
Kawasaki's disease is treated with high doses of aspirin (salicylic acid) to reduce inflammation and to mildly thin the blood to prevent blood clot formation. Also used in treatment is gamma globulin administered through the vein (intravenous immunoglobulin or IVIG), together with fluids. This treatment has been shown to decrease the chance of developing aneurysms in the coronary arteries. Sometimes cortisone medications are given. Persisting joint pains are treated with anti-inflammatory drugs, such as ibuprofen (Advil) or naproxen(Aleve).
Plasma exchange (plasmapheresis) has been reported as effective in patients who were not responding to aspirin and gammaglobulin. Plasmapheresis is a procedure whereby the patient's plasma is removed from the blood and replaced with protein-containing fluids. By taking out portions of the patient's plasma, the procedure also removes antibodies and proteins that are felt to be part of the immune reaction that is causing the inflammation of the disease. Kawasaki's disease that is not responding to the traditional aspirin and gammaglobulin treatments can be deadly. Medications that block the effects of TNF (tumor necrosis factor), one of the messenger molecules in the inflammatory response, are being studied for use in these situations. Examples of TNF-blocking drugs are infliximab (Remicade) and etanercept(Enbrel). Further research is needed to design treatment programs for those who are failing conventional treatments. Pentoxifylline (Trental) is also being studied as a possible treatment for Kawasaki's disease.
No comments:
Post a Comment